Compile Data Set for Download or QSAR
Found 249 of ic50 data for polymerid = 1592
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM258601(US9493490, 6-(4-(aminomethyl)-2-chlorophenoxy)-7-i...)copy SMILEScopy InChI
Affinity DataIC50: 0.0550nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R2109JUS Patent
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.935nMAssay Description:Inhibition of human PKA using LCGRTGRRNSI as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.58nMAssay Description:Inhibition of human PKACA using LCGRTGRRNSI as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM258598(US9493490, Example 10 | US9493490, G)copy SMILEScopy InChI
Affinity DataIC50: 1.79nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R2109JUS Patent
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Inhibition of PKACalpha (unknown origin) incubated for 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM258600(US9493490, 6-(3-(aminomethyl)-2-fluorophenoxy)-7-m...)copy SMILEScopy InChI
Affinity DataIC50: 3.38nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R2109JUS Patent
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM258595(US9493490, 6-(4-(aminomethyl)-2-fluorophenoxy)-7-m...)copy SMILEScopy InChI
Affinity DataIC50: 4.06nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R2109JUS Patent
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM50311410(CHEMBL1077376 | N-((5S,8R,11R,14R,17R,20R,23R,33R)...)copy SMILEScopy InChI
Affinity DataIC50: 4.90nMAssay Description:Inhibition of PKACalpha in presence of 1000 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM29R4PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM50199310(2S,3S,4R,5R)-5-6-amino-9H-purin-9-yl)-N-12R,15R,18...)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Inhibitory potency towards human cAPK C alpha in the presence of 100uM ATP and 30uM TAMRA-kemptideMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N79PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM50199310(2S,3S,4R,5R)-5-6-amino-9H-purin-9-yl)-N-12R,15R,18...)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Inhibitory potency towards human cAPK C alpha in the presence of 100uM ATP and 30uM TAMRA-kemptideMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N79PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM50311409(CHEMBL1077375 | N-((6R,9R,12R,15R,18R,21R,31R)-1-a...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Inhibition of PKACalpha in presence of 1000 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM29R4PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM50599148(CHEMBL5188777)copy SMILES
Affinity DataIC50: 5.60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3K3WPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM258596(US9493490, 6-(4-(1-aminoethyl)-2-fluorophenoxy)-7-...)copy SMILEScopy InChI
Affinity DataIC50: 6.09nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R2109JUS Patent
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM258599(US9493490, Example 11 | US9493490, L | US9493490, ...)copy SMILEScopy InChI
Affinity DataIC50: 7.88nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R2109JUS Patent
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM27248(6-{[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-di...)copy SMILEScopy InChI
Affinity DataIC50: 8.30nMAssay Description:Inhibitory potency towards human cAPK C alpha in the presence of 100uM ATP and 30uM TAMRA-kemptideMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N79PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM27248(6-{[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-di...)copy SMILEScopy InChI
Affinity DataIC50: 8.30nMAssay Description:Inhibitory potency towards human cAPK C alpha in the presence of 100uM ATP and 30uM TAMRA-kemptideMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N79PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM50242733(AT-13148)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human His-tagged PKA catalytic domain (1 to 351 residues) expressed in Escherichia coli using Ser/Thr 7 as substrate after ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70J7FPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM258597(US9493490, Example 9 | US9493490, F)copy SMILEScopy InChI
Affinity DataIC50: 11.0nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R2109JUS Patent
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM50219803(6-{[(1S,3R,4R)-3-(6-amino-9H-purin-9-yl)-4-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 12.9nMAssay Description:Inhibition of cAPK Calpha in presence of 0.1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9WBJPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM50311405(CHEMBL1077369 | N-((6R,9R,19R)-1-amino-19-(4-amino...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of PKACalpha in presense of 100 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM29R4PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM50599147(CHEMBL5201435)copy SMILES
Affinity DataIC50: 24nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3K3WPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM50536679(CHEMBL4568087)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant human His-tagged PRKACA catalytic domain expressed in Escherichia coli by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NP27X5PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)copy SMILES
Affinity DataIC50: 29nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)copy SMILES
Affinity DataIC50: 29nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM3153(2-{[2,6-dihydroxy-4-({[(1R,2R)-2-[(4-hydroxybenzen...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibitory concentration of the compound against recombinant human cAMP-dependent Protein kinase AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J965HRPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM3149(2-{[2,6-dihydroxy-4-({[(3R,4R)-3-[(4-hydroxybenzen...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration of the compound against recombinant human cAMP-dependent Protein kinase AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J965HRPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM50055668(4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benz...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration of the compound against recombinant human cAMP-dependent Protein kinase AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J965HRPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM258594(US9493490, 6-(4-(1-aminoethyl)-2-fluorophenoxy)ben...)copy SMILEScopy InChI
Affinity DataIC50: 50nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R2109JUS Patent
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM27225((2R)-6-amino-2-(6-{[(2S,3S,4R,5R)-5-(6-amino-9H-pu...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Inhibition of PKACalpha in presense of 100 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM29R4PubMedMMDB
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM50311407(CHEMBL1077371 | N-((6R,9R,19R)-1-amino-19-(4-amino...)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibition of PKACalpha in presense of 100 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM29R4PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM3152(2-{[2,6-dihydroxy-4-({[(3R,4R)-4-[(4-hydroxybenzen...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibitory concentration of the compound against recombinant human cAMP-dependent Protein kinase AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J965HRPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM511480(US11059789, Example 40 | US11691950, Example 40)copy SMILES
Affinity DataIC50: 71nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM511480(US11059789, Example 40 | US11691950, Example 40)copy SMILES
Affinity DataIC50: 71nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)copy SMILES
Affinity DataIC50: 81nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)copy SMILES
Affinity DataIC50: 81nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM50311405(CHEMBL1077369 | N-((6R,9R,19R)-1-amino-19-(4-amino...)copy SMILEScopy InChI
Affinity DataIC50: 82nMAssay Description:Inhibition of PKACalpha in presence of 1000 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM29R4PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM50055685(4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benz...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibitory concentration of the compound against recombinant human cAMP-dependent Protein kinase AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J965HRPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM50219805(6-{[(1R,3S,4S)-3-(6-amino-9H-purin-9-yl)-4-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 97.3nMAssay Description:Inhibition of cAPK Calpha in presence of 0.1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9WBJPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM511483(US11059789, Example 66 | US11691950, Example 66)copy SMILES
Affinity DataIC50: 117nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM511483(US11059789, Example 66 | US11691950, Example 66)copy SMILES
Affinity DataIC50: 117nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM50055684(4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benz...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibitory concentration of the compound against recombinant human cAMP-dependent Protein kinase AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J965HRPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM511481(US11059789, Example 25 | US11691950, Example 25)copy SMILES
Affinity DataIC50: 138nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM511481(US11059789, Example 25 | US11691950, Example 25)copy SMILES
Affinity DataIC50: 138nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM50055677(4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benz...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibitory concentration of the compound against recombinant human cAMP-dependent Protein kinase AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J965HRPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM25472(CHEMBL519123 | N-[4-(1H-pyrazol-4-yl)phenyl]-2,3-d...)copy SMILEScopy InChI
Affinity DataIC50: 186nMpH: 7.3 T: 2°CAssay Description:Reaction mixture of kemptide, ATP, and test compound was added to the wells using a BioRAPTR FRD Workstation (Aurora Discovery). Reaction was started...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9NRNPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM16591((4Z)-4-(2-amino-5-oxo-3,5-dihydro-4H-imidazol-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 190nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed in reaction buffer containing substrate peptide, enzyme, and inhibitor compound in the presence ATP/[gamma-33P] ATP. 33P ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F9KPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM50055681(4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benz...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibitory concentration of the compound against recombinant human cAMP-dependent Protein kinase AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J965HRPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM50055672(4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benz...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibitory concentration of the compound against recombinant human cAMP-dependent Protein kinase AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J965HRPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM50055676(4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benz...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibitory concentration of the compound against recombinant human cAMP-dependent Protein kinase AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J965HRPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM511485(US11059789, Example 27 | US11691950, Example 27)copy SMILES
Affinity DataIC50: 317nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
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